Letrozole 2.5mg 50 capsules

Letrozole 2.5 mg – Overview

Letrozole is a prescription medication classified as an aromatase inhibitor (AI). It is most commonly used in the treatment of hormone receptor–positive breast cancer in postmenopausal women. A 2.5 mg tablet is the standard pharmaceutical strength for medical use.

Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens (such as testosterone) into estrogen. By reducing estrogen production, letrozole lowers circulating estrogen levels in the body.

Mechanism of Action

• Drug Class: Non-steroidal aromatase inhibitor

• Primary Action: Blocks conversion of androgens to estrogen

• Result: Significant reduction in systemic estrogen levels

Because estrogen can stimulate certain breast cancer cells to grow, reducing estrogen levels can help slow or stop tumor progression in hormone-sensitive cases.

Medical Uses

Letrozole is commonly prescribed for:

• Treatment of hormone receptor–positive breast cancer in postmenopausal women

• Extended adjuvant therapy after tamoxifen

• Ovulation induction in certain fertility treatments (off-label use under medical supervision)

Potential Side Effects

By lowering estrogen levels, letrozole may cause:

• Joint pain or stiffness

• Hot flashes

• Fatigue

• Bone density reduction (increased osteoporosis risk)

• Elevated cholesterol in some individuals

• Headaches

Because estrogen plays an important role in bone health and cardiovascular protection, long-term use requires medical monitoring

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